Studies on IBD & fatty liver disease
Good morning everybody, so straight in today with some studies that have interest to many of you. Examining associations between protein intake and IBD. So the incidence of inflammatory bowel diseases, IBD such as Crohn's disease and ulcerative colitis has been on the rise prompting researchers to examine environmental factors that could contribute to increased risk of disease. Previous reports have indicated a possible link between protein intake and IBD risk, but another method analysis of IBD risk factors found the proteins association with IBD risk was relatively weak. This study further explored the associations between protein intake and IBD risk by examining total protein intake and the consumption of specific proteins in a large cohort of participants from 10 European countries.
Speaker 1:Okay. So in the cohort study, diet information from 413,000 participants in the European perspective investigation into cancer nutrition study was collected via food frequency questionnaire. The analysis, assessed the associations doing one, total protein intake and the consumption of protein from specific sources, animal or vegetable and two, IBD risk. So the results were after sixteen year follow-up period, 117 the participants developed CD and 418 developed UC. These were there were no associations between food sources or types of protein and CD.
Speaker 1:There were also no associations between consumption of total animal or vegetable protein and UC risk. However, total meat and red meat consumption were both associated with a forty-sixty percent increase in UC risk. There were no associations between other specific animal protein sources such as processed meat, fish, shellfish, eggs or poultry, and UC risk. The authors suggest that due to the association between UC risk and meat consumption, their results support diet counseling for people at high risk of IBD. That's interesting, So there has been a thing like high protein's bad, but it's not so much the protein, it's the specific protein it seems and the red meat, total meat and red meat.
Speaker 1:So, you know, red meat in itself has always been, suggested to be eaten in moderation, hasn't it? It's not something you should eat every day that this has been quite like this is known knowledge, red meat minimal. So if you are at risk or you've got Crohn's or electrolytes whatever, it might be worth bringing a study up to the specialist you speak to, maybe reducing your meat intake while still trying to get protein in but you know in other methods that could be of use or trial and at least. The next study staying on point, the Mediterranean diet for children with IBD, so inflammatory bowel disease. So background is several studies have reported beneficial effects of a Mediterranean diet on inflammatory bowel disease for adults, but studies in children adolescents are lacking.
Speaker 1:The study in this twelve week randomized controlled trial, 100 children and adolescents aged 12 to 18 who had Crohn's disease or UC with mid to moderate disease activity consumed either a Mediterranean diet or the regular diet whilst receiving treatment for IBD. The main outcomes are clinical disease scores measured with the pediatric Crohn's disease activity index PCDAI and the pediatric ulcerative colitis activity index PUCAI and several biomarkers of inflammation. Here are the results. Most of the participants achieved clinical remission of IBD symptoms by the end of the study, so forty six in the Mediterranean group versus thirty nine in the control group. Mediterranean diet was more effective than a regular diet for improving clinical scores and slamming some inflammatory markers, so reactive protein tumor necrosis factor alpha, you don't even know that.
Speaker 1:So both of them with the right treatment helped, you know forty six versus thirty nine, Right? A slight improvement in the Mediterranean diet. As we know, the Mediterranean diet, you know, this good fats, a lot of veggies, you know, not loads and loads of meat, but, you know, they still eat meat. That diet is always a good choice. Like, you wanna the advice with Turtle, if you wanna lose fat, you don't have to fight food and eat hey, don't eat the food you love.
Speaker 1:But as time goes on and we see and we we have compassion for our bodies and love for our bodies and all stuff, we go, you know what? I've lost the weight now. Food isn't a problem for me, but I genuinely want to eat a higher quality diet. And when you genuinely want to eat a higher quality diet because you actually want to, not because you think you have to lose weight, that changes the game completely. And that's why that's the route to go down.
Speaker 1:So, yeah, that's, interesting two studies there. There's another one I'm gonna share with you. Let me get the notes up about it. Okay, here we go. Does skipping breakfast increase cardiovascular disease mortality in individuals with MAFLD?
Speaker 1:So metabolic dysfunctional associated liver disease, formerly known as non alcoholic fatty liver disease, increase the risk for cardiovascular disease and mortality, morbidity and mortality. So calorie restriction is recommended for the treatment of this non alcoholic fatty liver. And how this calorie restriction should be achieved remains unclear. Skipping breakfast is one strategy used to reduce daily calorie intake, yet several studies have associated breakfast skipping with the greater risk of obesity, type two diabetes, and cardiovascular disease. Knowing how different patterns of breakfast consume influence health outcomes in individuals with, non alcoholic fatty liver disease is important.
Speaker 1:The study, like looked at the study, average age 42, 10,000 people. The participants breakfast consumed was assessed using response to the question how often do you eat breakfast. The results in the entire cohort breakfast skipping was associated with nearly two times greater risk of cardiovascular mortality. However, when the participants were separated by non alcoholic fatty liver disease breakfast skipping was associated with cardiovascular mortality only in that group. Okay, So compared to participants with non alcoholic fatty liver disease who ate breakfast every day, those who never ate breakfast have a two point eight times the risk of cardiovascular mortality, five point five times the risk of cerebrovascular mortality, and two point two times the risk for heart disease mortality.
Speaker 1:These associations were independent of total daily calorie intake. So if you don't have low, if you don't have non alcoholic fatty liver disease, there was no association, no problem. But if you do have it, it is likely that you need to eat breakfast from this study. It's clear you need to go and still eat breakfast. Get good quality breakfast.
Speaker 1:Limitation of this study is a breakfast consumption were assessed using a single response to a twenty four hour dietary recall questionnaire which may not fully capture the participants usually dietary habits. Three interesting studies are. What do we learn from three of them? Well, very sort of had them they were very specific studies. But obviously, Louise got UC, more people have got There needs to be a there needs to be a chat about it.
Speaker 1:There needs to be more discussion about it for sure. It tends to impact women more than men. So hopefully that study was useful. And we've spoken to people on Turtle Method who have got, nonalcoholic fatty liver disease as well. And hopefully that's useful.
Speaker 1:Like, if you're skipping breakfast, maybe it's time to not skip breakfast. Like doctor Id said in his q and a as well, like making sure you eat your calories earlier in the day is better than later. For health reasons, he's independent from fat loss goals with different things. Right? So maybe it's time to bring that breakfast back in.
Speaker 1:If you have got non alcoholic fatty liver disease, which again yo yo dieting is seen to be in association with that as well. So if you yo yo diet, you are at risk higher risk of non alcoholic fatty liver disease, right? So it all intertwines, you know, completely. So hopefully that was useful. Basically the crux is if we break it down, eat if you haven't got any problems and you're trying to lose weight, you can eat your calories and everything.
Speaker 1:If you have got problems, like non alcoholic fatty liver, UC and all this stuff, then you have to be more specific with your eating. You actually have to look at these things. Alright? Unfortunately, it's the kind of freedom is less because these symptoms are there. There's another study as well before I finish on, fibre and, UC as well so evidence suggests the fibre supplements may help in the management of UC and autoimmune inflammatory bowel disease however the role of non supplementary dietary fibre I.
Speaker 1:E. Fibre through your food is less clear. The cross sectional study examined the association between the amount of non supplement fibre in the regular diet and ongoing disease activity in faulty Mexican adults with UC, divided in two groups. They were met the recommended fibre intake of fourteen grams per thousand and if you look at your macro app, Turtle Macro app, that's what we do for you as well, fibre intake on that. The researchers assessed dietary intake using a questionnaire la la la.
Speaker 1:Okay results, consuming fourteen grams of dietary fibre per thousand calories was associated with lower odds of ongoing overall disease activity, specifically biochemical activity. Moreover the researchers detected an inverse association between dietary fiber intake and the number of disease relapses within the previous year, which means a greater intake of dietary fiber was linked to a smaller number of relapses. Okay, small study but again fiber is important, that's where we track macros, fiber is tracked under the carbs umbrella. So get your fiber in. Let's go through this again now.
Speaker 1:Get your fiber in, right, eat more like a Mediterranean diet if possible, know, we got those Mediterranean chicken recipe you can go with, which I love is the those veggies and the chicken amazing in olive oil. Don't cook with olive oil. Put the wrong cold like they do over there, which make sure the fat is intact. All also eat your favorite foods, of course, and balancing it all out, but we eat for health. We eat to get you know, we eat for health.
Speaker 1:And then there's another independent where losing fat improves our health as well. You lose 10% of your body weight, your health improves. And then we need to look at over time improving the quality of our diet, but hopefully those studies were interesting. If you know anyone with UC or stuff like that, maybe send them the link to this to have a listen. But I will link the studies out if people do wanna have a read of them.
Speaker 1:But have a good day, basically. It's a Monday. It's time to go again. We're twenty four hours ahead of us. Well, one day, whatever it is.
Speaker 1:What time you wake up depends on it. So can't be complaining, can't be victims. We gotta go on. We gotta go on with our days today. We gotta gotta do the next task.
Speaker 1:We gotta make it a positive next task and build momentum today. Otherwise, we're gonna go backwards. So build momentum, enjoy like, fun with the day, you know. Have fun tracking. It is quite fun.
Speaker 1:I tracked I went to the cinema, right, on let me get it up. So on Saturday, I went to cinema, but before that, I had a few pints, then I I went to Wagamama, and then I went to the cinema at a bag of Maltesers. Right. Let me just let me just show you the crazy. Okay.
Speaker 1:So I had two and a half pints, okay. Yeah the third pint was horrible. That's 587 calories. I had the I had the Maltesers bag, 700 calories, and then I had the Chicken Katsu Curry which was eleven forty nine calories. So in that I had 1,008 2,300 calories and then I had a Korean barbecue beef I had the beef buns as well, 260 2,600 calories and then the gyoza as I had two seventy five two thousand seven hundred and fifty calories.
Speaker 1:So my one meal out and some drinks equaled 2,700 calories. I'm sad about it. I was just like, wow, just wow, ain't it? Fair play. Fair play.
Speaker 1:You really it really is easy to to consume a lot of calories. So hopefully, the calories and menus are helping you realize this as well, guys. But, enjoy your day. See you in the radio. Our next challenge starts week today.
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Speaker 1:So enjoy your day. Speak to you soon.
